Article
A genomewide admixture map for Latino populations.
American journal of human genetics - 1 Jun 2007
Price Alkes L, Patterson Nick, Yu Fuli, Cox David R, Waliszewska Alicja, McDonald Gavin J, Tandon Arti, Schirmer Christine, Neubauer Julie, Bedoya Gabriel, Duque Constanza, Villegas Alberto, Bortolini Maria Catira, Salzano Francisco M, Gallo Carla, Mazzotti Guido, Tello-Ruiz Marcela, Riba Laura, Aguilar-Salinas Carlos A, Canizales-Quinteros Samuel, Menjivar Marta, Klitz William, Henderson Brian, Haiman Christopher A, Winkler Cheryl, Tusie-Luna Teresa, Ruiz-Linares Andres, Reich David
Abstract excerpt
Admixture mapping is an economical and powerful approach for localizing disease genes in populations of recently mixed ancestry and has proven successful in African Americans. The method holds equal promise for Latinos, who typically inherit a mix of European, Native American, and African ancestry. However, admixture mapping in Latinos has not been practical because of the lack of a map of ancestry-informative...
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