Article
Local and global ancestry inference and applications to genetic association analysis for admixed populations.
Genetic epidemiology - 1 Sept 2014
Thornton Timothy A, Bermejo Justo Lorenzo
Abstract excerpt
Genetic association studies in recently admixed populations offer exciting opportunities to identify novel variants underlying phenotypic diversity. At the same time, genetic heterogeneity resulting from population admixture has to be accounted for to ensure validity of association tests. The whole-genome sequence data and the genome-wide single-nucleotide polymorphism chip data for Mexican American individuals...
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