Article
Idiosyncratic drug-induced agranulocytosis: possible mechanisms and management.
American journal of hematology - 1 Jul 2009
Tesfa Daniel, Keisu Marianne, Palmblad Jan
Abstract excerpt
The incidence of drug-induced neutropenia has not changed in the western hemisphere over the last 30 years. Yet, the drug panorama has changed considerably. This implies that host factors may play an intriguing role for this idiosyncratic reaction. The knowledge as to mechanisms for the reaction has advanced with emerging understanding of neutropoiesis and immune regulation. Nonetheless, it is still remarkably...
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