Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

hotspot: software to support sperm-typing for investigating recombination hotspots.

Bioinformatics (Oxford, England) - 15 Aug 2016

Odenthal-Hesse Linda, Dutheil Julien Y, Klötzl Fabian, Haubold Bernhard

Abstract excerpt

MOTIVATION: In many organisms, including humans, recombination clusters within recombination hotspots. The standard method for de novo detection of recombinants at hotspots is sperm typing. This relies on allele-specific PCR at single nucleotide polymorphisms. Designing allele-specific primers by hand is time-consuming. We have therefore written a package to support hotspot detection and analysis. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Likelihood Functions
Share to Recombination, Genetic

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Software

Share to Spermatozoa

Source

Open in PubMed Open full text

Identifiers

PMID: 27153632
DOI: 10.1093/bioinformatics/btw195
PMCID: PMC4978934

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

hotspot: software to support sperm-typing for investigating recombination hotspots.PMID 27153632Read ↗

Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome.Semantic proximity Read ↗

Meiotic recombination hot spots and human DNA diversity.Semantic proximity Read ↗

inGAP-family: Accurate Detection of Meiotic Recombination Loci and Causal Mutations by Filtering Out Artificial Variants due to Genome Complexities.Semantic proximity Read ↗

Mammalian meiotic recombination hot spots.Semantic proximity Read ↗

Insights into recombination from population genetic variation.Semantic proximity Read ↗

A new method to reconstruct recombination events at a genomic scale.Semantic proximity Read ↗

The rise and fall of a human recombination hot spot.Semantic proximity Read ↗

Detecting Recombination Hotspots from Patterns of Linkage Disequilibrium.Semantic proximity Read ↗

sgcocaller and comapr: personalised haplotype assembly and comparative crossover map analysis using single-gamete sequencing data.Semantic proximity Read ↗

A novel method with improved power to detect recombination hotspots from polymorphism data reveals multiple hotspots in human genes.Semantic proximity Read ↗

Why recombination hotspots?Semantic proximity Read ↗

Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.