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Article

Detecting sequence polymorphisms associated with meiotic recombination hotspots in the human genome.

Genome biology - 1 Jan 2010

Zheng Jie, Khil Pavel P, Camerini-Otero R Daniel, Przytycka Teresa M

Abstract excerpt

BACKGROUND: Meiotic recombination events tend to cluster into narrow spans of a few kilobases long, called recombination hotspots. Such hotspots are not conserved between human and chimpanzee and vary between different human ethnic groups. At the same time, recombination hotspots are heritable. Previous studies showed instances where differences in recombination rate could be associated with sequence...

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Identifiers

PMID: 20961408
DOI: 10.1186/gb-2010-11-10-r103
PMCID: PMC3218659

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DNA2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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