Article
Detecting Recombination Hotspots from Patterns of Linkage Disequilibrium.
G3 (Bethesda, Md.) - 9 Aug 2016
Wall Jeffrey D, Stevison Laurie S
Abstract excerpt
With recent advances in DNA sequencing technologies, it has become increasingly easy to use whole-genome sequencing of unrelated individuals to assay patterns of linkage disequilibrium (LD) across the genome. One type of analysis that is commonly performed is to estimate local recombination rates and identify recombination hotspots from patterns of LD. One method for detecting recombination hotspots, LDhot, has...
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