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Article

Critical assessment of coalescent simulators in modeling recombination hotspots in genomic sequences.

BMC bioinformatics - 3 Jan 2014

Yang Tao, Deng Hong-Wen, Niu Tianhua

Abstract excerpt

BACKGROUND: Coalescent simulation is pivotal for understanding population evolutionary models and demographic histories, as well as for developing novel analytical methods for genetic association studies for DNA sequence data. A plethora of coalescent simulators are developed, but selecting the most appropriate program remains challenging. RESULTS: We extensively compared performances of five widely used...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24387001
DOI: 10.1186/1471-2105-15-3
PMCID: PMC3890628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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