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Article

RNA polymerase III component Rpc9 regulates hematopoietic stem and progenitor cell maintenance in zebrafish.

Development (Cambridge, England) - 15 Jun 2016

Wei Yonglong, Xu Jin, Zhang Wenqing, Wen Zilong, Liu Feng

Abstract excerpt

Hematopoietic stem and progenitor cells (HSPCs) are capable of self-renewal and replenishing all lineages of blood cells throughout life and are thus crucial for tissue homeostasis. However, the mechanism regulating HSPC development is still incompletely understood. Here, we isolate a zebrafish mutant with defective T lymphopoiesis and positional cloning identifies that Rpc9, a component of DNA-directed RNA...

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Identifiers

PMID: 27151951
DOI: 10.1242/dev.126797

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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