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Article

Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.

Experimental hematology - 1 Mar 2012

Taylor Alison M, Humphries Jessica M, White Richard M, Murphey Ryan D, Burns Caroline E, Zon Leonard I

Abstract excerpt

Disruption of ribosomal proteins is associated with hematopoietic phenotypes in cell culture and animal models. Mutations in ribosomal proteins are seen in patients with Diamond Blackfan anemia, a rare congenital disease characterized by red cell aplasia and distinctive craniofacial anomalies. A zebrafish screen uncovered decreased hematopoietic stem cells in embryos with mutations in ribosomal protein rps29....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22120640
DOI: 10.1016/j.exphem.2011.11.007
PMCID: PMC3310385

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Hematopoietic defects in rps29 mutant zebrafish depend upon p53 activation.PMID 22120640Read ↗

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