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Article

Evolved resistance to colistin and its loss due to genetic reversion in Pseudomonas aeruginosa.

Scientific reports - 6 May 2016

Lee Ji-Young, Park Young Kyoung, Chung Eun Seon, Na In Young, Ko Kwan Soo

Abstract excerpt

The increased reliance on colistin for treating multidrug-resistant Gram-negative bacterial infections has resulted in the emergence of colistin-resistant Pseudomonas aeruginosa. We attempted to identify genetic contributors to colistin resistance in vitro evolved isogenic colistin-resistant and -susceptible strains of two P. aeruginosa lineages (P5 and P155). Their evolutionary paths to acquisition and loss of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 27150578
DOI: 10.1038/srep25543
PMCID: PMC4858706

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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