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Article

Interplay between Colistin Resistance, Virulence and Fitness in Acinetobacter baumannii

21 Nov 2017

Abstract excerpt

Acinetobacter baumannii is an important opportunistic nosocomial pathogen often resistant to multiple antibiotics classes. Colistin, an “old” antibiotic, is now considered a last-line treatment option for extremely resistant isolates. In the meantime, resistance to colistin has been reported in clinical A. baumannii strains. Colistin is a cationic peptide that disrupts the outer membrane (OM) of Gram-negative...

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PMID: 29160808
DOI: 10.3390/antibiotics6040028

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