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Article

Steady-state pharmacokinetics of sirolimus in stable adult Chinese renal transplant patients.

Clinical pharmacology in drug development - 1 May 2014

Wang Huifen Faye, Qiu Feng, Wu Xiongfe, Fang Juanzhi, Crownover Penelope, Korth-Bradley Joan, Schulman Seth

Abstract excerpt

This open-label, nonrandomized study was conducted to evaluate the steady-state pharmacokinetics of sirolimus in 24 stable Chinese renal transplant patients receiving daily oral maintenance doses of sirolimus (1-4 mg). Repeated trough and serial whole blood sirolimus concentrations over a 24-hour dosing interval were collected and assayed using high-performance liquid chromatography with tandem mass spectrometry...

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PMID: 27128614
DOI: 10.1002/cpdd.96

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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