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Article

Influence of everolimus on the pharmacokinetics of tacrolimus in Japanese renal transplant patients.

International journal of urology : official journal of the Japanese Urological Association - 1 Jun 2016

Niioka Takenori, Kagaya Hideaki, Saito Mitsuru, Inoue Takamitsu, Numakura Kazuyuki, Yamamoto Ryohei, Akamine Yumiko, Habuchi Tomonori, Satoh Shigeru, Miura Masatomo

Abstract excerpt

OBJECTIVES: To examine whether a trough concentration of everolimus in the therapeutic range of 3-5 ng/mL affects the pharmacokinetics of tacrolimus in renal transplant patients. METHODS: A total of 52 Japanese renal transplant patients receiving tacrolimus were enrolled in this study. In 28 of them, everolimus was co-administered on day 14 after surgery. Changes in the dose-adjusted blood trough concentration of...

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Identifiers

PMID: 26990259
DOI: 10.1111/iju.13081

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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