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Article

Temporal decline in sirolimus elimination immediately after pancreatic islet transplantation.

Drug metabolism and pharmacokinetics - 1 Dec 2006

Sato Eriko, Shimomura Masahiro, Masuda Satohiro, Yano Ikuko, Katsura Toshiya, Matsumoto Shin-ichi, Okitsu Teru, Iwanaga Yasuhiro, Noguchi Hirofumi, Nagata Hideo, Yonekawa Yukihide, Inui Ken-ichi

Abstract excerpt

Pancreatic islet transplantation is a curable treatment for type 1 diabetes and has been put into practice in various countries. In this study, we analyzed the pharmacokinetic characteristics of sirolimus and tacrolimus in six Japanese patients with pancreatic islet transplants immediately after surgery, and monitored efficacy and toxicity. The patients were treated with immunosuppressive therapy based on the...

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PMID: 17220565
DOI: 10.2133/dmpk.21.492

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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