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Article

Frequency and prognostic significance of t(v;11q23)/KMT2A rearrangements in adult patients with acute lymphoblastic leukemia treated with risk-adapted protocols.

Leukemia & lymphoma - 1 Jan 2017

Motlló Cristina, Ribera Josep-Maria, Morgades Mireia, Granada Isabel, Montesinos Pau, Brunet Salut, Bergua Juan, Tormo Mar, García-Boyero Raimundo, Sarrà Josep, Del Potro Eloy, Grande Carlos, Barba Pere, Bernal Teresa, Amigo María-Luz, Grau Javier, Cervera José, Feliu Evarist

Abstract excerpt

The karyotype is an important predictor of outcome in acute lymphoblastic leukemia (ALL). Rearrangements of the 11q23 region involving the KMT2A gene confer an unfavorable prognosis. Forty-six adult ALL patients from the PETHEMA Group treated with risk-adapted protocols, with t(v;11q23) were selected for this study. Complete response (CR) was attained in 38 patients; 25 remained in CR after consolidation. Twelve...

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PMID: 27122129
DOI: 10.1080/10428194.2016.1177182

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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