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Article

Cytogenetics of childhood acute myeloid leukemia: United Kingdom Medical Research Council Treatment trials AML 10 and 12.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Jun 2010

Harrison Christine J, Hills Robert K, Moorman Anthony V, Grimwade David J, Hann Ian, Webb David K H, Wheatley Keith, de Graaf Siebold S N, van den Berg Eva, Burnett Alan K, Gibson Brenda E S

Abstract excerpt

PURPOSE: Karyotype is an independent indicator of prognosis in acute myeloid leukemia (AML) that is widely applied to risk-adapted therapy. Because AML is rare in children, the true prognostic significance of individual chromosomal abnormalities in this age group remains unclear. PATIENTS AND METHODS: This cytogenetic study of 729 childhood patients classified them into 22 subgroups and evaluated their incidence...

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PMID: 20439644
DOI: 10.1200/JCO.2009.24.8997

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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