Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Is acute lymphoblastic leukemia with mature B-cell phenotype and KMT2A rearrangements a new entity? A systematic review and meta-analysis.

Leukemia & lymphoma - 1 Sept 2021

Hidalgo-Gómez Gloria, Palacio-Garcia Carlos, Gallur Laura, Blanco Adoración, Tazón-Vega Bárbara, Saumell Silvia, Martínez Noemí, Murillo Laura, Murciano Thais, Velasco Pablo, Bosch Francesc, Diaz-Heredia Cristina, Ortega Margarita

Abstract excerpt

The association between mature B-cell phenotype and KMT2A rearrangements in acute lymphoblastic leukemia is a very rare finding. It identifies a group of patients with similar clinical and biological characteristics that clearly differs from the entity B-cell lymphoblastic leukemia/lymphoma with t(v;11q23)/KMT2A-rearranged, which typically presents an immature pro B-cell phenotype. We describe the...

Topics

Join the communities discussing this publication.

B-Lymphocytes
Infant
Phenotype
Precursor Cell Lymphoblastic Leukemia-Lymphoma

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33827367
DOI: 10.1080/10428194.2021.1907375

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Is acute lymphoblastic leukemia with mature B-cell phenotype and KMT2A rearrangements a new entity? A systematic review and meta-analysis.PMID 33827367Read ↗

Updates in KMT2A Gene Rearrangement in Pediatric Acute Lymphoblastic LeukemiaSemantic proximity Read ↗

Clinicopathologic and genetic spectrum of infantile B-lymphoblastic leukemia: a multi-institutional study.Semantic proximity Read ↗

KMT2A rearranged acute lymphoblastic leukaemia: Unravelling the genomic complexity and heterogeneity of this high-risk disease.Semantic proximity Read ↗

MLL-Rearranged Acute Lymphoblastic Leukemia.Semantic proximity Read ↗

KMT2A (MLL) rearrangements observed in pediatric/young adult T‐lymphoblastic leukemia/lymphoma: A 10‐year review from a single cytogenetic laboratorySemantic proximity Read ↗

Pediatric therapy-related hematologic neoplasms show enrichment for KMT2A rearrangement and lymphoblastic phenotype.Semantic proximity Read ↗

Molecular characterization and biomarker identification in paediatric B-cell acute lymphoblastic leukaemia.Semantic proximity Read ↗

Outcomes of acute lymphoblastic leukemia with KMT2A (MLL) rearrangement: the MD Anderson experienceSemantic proximity Read ↗

KMT2A Rearrangements in Leukemias: Molecular Aspects and Therapeutic PerspectivesSemantic proximity Read ↗

Updates in the biology and therapy for infant acute lymphoblastic leukemiaSemantic proximity Read ↗

Single-cell transcriptomics reveals a distinct developmental state of KMT2A-rearranged infant B-cell acute lymphoblastic leukemia.Semantic proximity Read ↗

Optimized cytogenetic risk-group stratification of KMT2A -rearranged pediatric acute myeloid leukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.