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Article

Maternal Loss of Ube3a Impairs Experience-Driven Dendritic Spine Maintenance in the Developing Visual Cortex.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 27 Apr 2016

Kim Hyojin, Kunz Portia A, Mooney Richard, Philpot Benjamin D, Smith Spencer L

Abstract excerpt

UNLABELLED: Dendritic spines are a morphological feature of the majority of excitatory synapses in the mammalian neocortex and are motile structures with shapes and lifetimes that change throughout development. Proper cortical development and function, including cortical contributions to learning and memory formation, require appropriate experience-dependent dendritic spine remodeling. Dendritic spine...

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Identifiers

PMID: 27122043
DOI: 10.1523/JNEUROSCI.4204-15.2016
PMCID: PMC4846678

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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