Article
Neural cell adhesion molecule NrCAM regulates Semaphorin 3F-induced dendritic spine remodeling.
The Journal of neuroscience : the official journal of the Society for Neuroscience - 20 Aug 2014
Demyanenko Galina P, Mohan Vishwa, Zhang Xuying, Brennaman Leann H, Dharbal Katherine E S, Tran Tracy S, Manis Paul B, Maness Patricia F
Abstract excerpt
Neuron-glial related cell adhesion molecule (NrCAM) is a regulator of axon growth and repellent guidance, and has been implicated in autism spectrum disorders. Here a novel postsynaptic role for NrCAM in Semaphorin3F (Sema3F)-induced dendritic spine remodeling was identified in pyramidal neurons of the primary visual cortex (V1). NrCAM localized to dendritic spines of star pyramidal cells in postnatal V1, where...
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