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Article

Integrin β3 organizes dendritic complexity of cerebral cortical pyramidal neurons along a tangential gradient.

Molecular brain - 14 Dec 2020

Swinehart Brian D, Bland Katherine M, Holley Z Logan, Lopuch Andrew J, Casey Zachary O, Handwerk Christopher J, Vidal George S

Abstract excerpt

Dysfunctional dendritic arborization is a key feature of many developmental neurological disorders. Across various human brain regions, basal dendritic complexity is known to increase along a caudal-to-rostral gradient. We recently discovered that basal dendritic complexity of layer II/III cortical pyramidal neurons in the mouse increases along a caudomedial-to-rostrolateral gradient spanning multiple regions,...

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Identifiers

PMID: 33317577
DOI: 10.1186/s13041-020-00707-0
PMCID: PMC7734815

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