Article

Dysfunctional synaptic competition at dendritic spines in Fragile X syndrome

2026-02-26

Abstract excerpt

Dendritic spines are highly dynamic structures whose morphology and lifespan are modified in response to synaptic efficacy changes. Structural modifications following activity support the long-term encoding of information and could allow for the remodeling of neural circuits. Long-term depression (LTD) is a key mechanism for synaptic weight regulation, yet its structural correlates — particularly for long-lasting,...

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Literature Corpus work: 584a94aa-316b-5dcf-9944-fcf032e0af73
DOI: 10.64898/2026.02.25.708113

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