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Article

Botulinum neurotoxin type C protease induces apoptosis in differentiated human neuroblastoma cells.

Oncotarget - 31 May 2016

Rust Aleksander, Leese Charlotte, Binz Thomas, Davletov Bazbek

Abstract excerpt

Neuroblastomas constitute a major cause of cancer-related deaths in young children. In recent years, a number of translation-inhibiting enzymes have been evaluated for killing neuroblastoma cells. Here we investigated the potential vulnerability of human neuroblastoma cells to protease activity derived from botulinum neurotoxin type C. We show that following retinoic acid treatment, human neuroblastoma cells,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 27121208
DOI: 10.18632/oncotarget.8903
PMCID: PMC5078088

Genes

SNAP25
SNAP23

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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