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Article

Senataxin modulates neurite growth through fibroblast growth factor 8 signalling.

Brain : a journal of neurology - 1 Jun 2011

Vantaggiato Chiara, Bondioni Sara, Airoldi Giovanni, Bozzato Andrea, Borsani Giuseppe, Rugarli Elena I, Bresolin Nereo, Clementi Emilio, Bassi Maria Teresa

Abstract excerpt

Senataxin is encoded by the SETX gene and is mainly involved in two different neurodegenerative diseases, the dominant juvenile form of amyotrophic lateral sclerosis type 4 and a recessive form of ataxia with oculomotor apraxia type 2. Based on protein homology, senataxin is predicted to be a put...

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Source

Identifiers

PMID: 21576111
DOI: 10.1093/brain/awr084

Genes

SETX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-21576111-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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