Article
Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach.
Immunology letters - 1 Jun 2016
Gupta Usha, Mir Snober S, Garg Naveen, Agarwal Surendra K, Pande Shantanu, Mittal Balraj
Abstract excerpt
Rheumatic heart disease (RHD) is an inflammatory, autoimmune disease; occurring as a consequence of group A streptococcal infection complicated by rheumatic fever (RF). An inappropriate immune response is the central signature tune to the complex pathogenesis of RHD. However, some of those infected develop RHD, and genetic host susceptibility factors are thought to play a key role in diseasedevelopment....
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