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Article

A study on the association of TNF-α(-308), IL-6(-174), IL-10(-1082) and IL-1Ra(VNTR) gene polymorphisms with rheumatic heart disease in Pakistani patients.

Cytokine - 1 Feb 2013

Rehman Sadia, Akhtar Naveed, Saba Nusrat, Munir Saeeda, Ahmed Waqar, Mohyuddin Aisha, Khanum Azra

Abstract excerpt

Inflammation is an important contributor to the pathogenesis of rheumatic heart disease (RHD), a disorder of heart valves caused by a combination of immune, genetic and environmental factors. Cytokines are important mediators of inflammatory and immune responses. The aim of this study was to investigate the role of cytokine gene polymorphisms and their potential usefulness as biomarkers in RHD patients from...

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Source

Identifiers

PMID: 23168096
DOI: 10.1016/j.cyto.2012.10.020

Genes

RHD
TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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