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Article

Signal transducers and activators of transcription (STATs) gene polymorphisms related with susceptibility to rheumatic heart disease in north Indian population.

Immunology letters - 1 Sept 2014

Gupta Usha, Mir Snober S, Srivastava Apurva, Garg Naveen, Agarwal Surendra K, Pande Shantanu, Mittal Balraj

Abstract excerpt

Rheumatic heart disease (RHD) is the most serious complication of heart that comprises inflammatory reactions in heart valves. Cytokines play a critical role in triggering inflammatory reactions and they activate the Janus Kinase/Signal Transducers and Activators of Transcription (JAK/STAT) signaling pathway. Altered signals of STATs play important roles in the balance between proinflammatory and...

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Source

Identifiers

PMID: 24797343
DOI: 10.1016/j.imlet.2014.04.015

Genes

RHD
STAT3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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