Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene polymorphisms of TNF-alpha(-308), IL-10(-1082), IL-6(-174), and IL-1Ra(VNTR) related to susceptibility and severity of rheumatic heart disease.

Pediatric cardiology - 1 Jan 2000

Settin A, Abdel-Hady H, El-Baz R, Saber I

Abstract excerpt

Rheumatic heart disease (RHD) is an inflammatory disease of the heart tissues caused by interactive immune, genetic, and environmental factors. The objective of this study is to test for the association of polymorphisms related to cytokine genes with susceptibility and severity of RHD among affected children from the Nile Delta region of Egypt. The study included 50 children with chronic RHD (29 males and 21...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Egypt
Share to Heart Valve Diseases
Share to Interleukin 1 Receptor Antagonist Protein

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Interleukin-10

Share to Interleukin-6

Share to Minisatellite Repeats

Share to Rheumatic Heart Disease

Share to Tumor Necrosis Factor-alpha

Source

Identifiers

PMID: 17607501
DOI: 10.1007/s00246-006-0002-7

Genes

TNF
RHD
MVD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene polymorphisms of TNF-alpha(-308), IL-10(-1082), IL-6(-174), and IL-1Ra(VNTR) related to susceptibility and severity of rheumatic heart disease.PMID 17607501Read ↗

A study on the association of TNF-α(-308), IL-6(-174), IL-10(-1082) and IL-1Ra(VNTR) gene polymorphisms with rheumatic heart disease in Pakistani patients.Semantic proximity Read ↗

Association of tumor necrosis factor-alpha polymorphisms with susceptibility and clinical outcomes of rheumatic heart disease.Semantic proximity Read ↗

Association of IL-4 (intron 3) and IL-10 (-1082) gene polymorphisms with risk of mitral valve disease in children with rheumatic heart disease.Semantic proximity Read ↗

Inflammatory Response Genes’ Polymorphism Associated with Risk of Rheumatic Heart DiseaseSemantic proximity Read ↗

Association study of inflammatory genes with rheumatic heart disease in North Indian population: A multi-analytical approach.Semantic proximity Read ↗

Tumor necrosis factor-alpha 308G>A polymorphism and risk of rheumatic heart disease: a meta-analysis.Semantic proximity Read ↗

Association Between the Interferon Gamma 874 T/A Polymorphism and the Severity of Valvular Damage in Patients with Rheumatic Heart Disease.Semantic proximity Read ↗

Genetic variants in rheumatic fever and rheumatic heart disease.Semantic proximity Read ↗

Role of cytokine gene (IFN-γ, TNF-α, TGF-β1, IL-6, and IL-10) polymorphisms in pathogenesis of acute rheumatic fever in Turkish children.Semantic proximity Read ↗

Tumor necrosis factor-alpha promoter polymorphisms in Mexican patients with rheumatic heart disease.Semantic proximity Read ↗

Transforming growth factor-beta1 gene C-509T and T869C polymorphisms as possible risk factors in rheumatic heart disease in Egypt.Semantic proximity Read ↗

Interleukin-10: Role in increasing susceptibility and pathogenesis of rheumatic fever/rheumatic heart disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.