Article
Brief Report: IRF4 Newly Identified as a Common Susceptibility Locus for Systemic Sclerosis and Rheumatoid Arthritis in a Cross-Disease Meta-Analysis of Genome-Wide Association Studies.
Arthritis & rheumatology (Hoboken, N.J.) - 1 Sept 2016
López-Isac Elena, Martín Jose-Ezequiel, Assassi Shervin, Simeón Carmen P, Carreira Patricia, Ortego-Centeno Norberto, Freire Mayka, Beltrán Emma, Narváez Javier, Alegre-Sancho Juan J, Fernández-Gutiérrez Benjamín, Balsa Alejandro, Ortiz Ana M, González-Gay Miguel A, Beretta Lorenzo, Santaniello Alessandro, Bellocchi Chiara, Lunardi Claudio, Moroncini Gianluca, Gabrielli Armando, Witte Torsten, Hunzelmann Nicolas, Distler Jörg H W, Riekemasten Gabriella, van der Helm-van Mil Annette H, de Vries-Bouwstra Jeska, Magro-Checa Cesar, Voskuyl Alexandre E, Vonk Madelon C, Molberg Øyvind, Merriman Tony, Hesselstrand Roger, Nordin Annika, Padyukov Leonid, Herrick Ariane, Eyre Steve, Koeleman Bobby P C, Denton Christopher P, Fonseca Carmen, Radstake Timothy R D J, Worthington Jane, Mayes Maureen D, Martín Javier
Abstract excerpt
OBJECTIVE: Systemic sclerosis (SSc) and rheumatoid arthritis (RA) are autoimmune diseases that have similar clinical and immunologic characteristics. To date, several shared SSc-RA genetic loci have been identified independently. The aim of the current study was to systematically search for new common SSc-RA loci through an interdisease meta-genome-wide association (meta-GWAS) strategy. METHODS: The study was...
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