Polymorphisms in STAT4 and IRF5 increase the risk of systemic sclerosis: a meta-analysis.

doi:10.1111/ijd.12839

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Article

Polymorphisms in STAT4 and IRF5 increase the risk of systemic sclerosis: a meta-analysis.

International journal of dermatology - 1 Apr 2016

Xu Yang, Wang Wenling, Tian Yanli, Liu Jingyang, Yang Rongya

Abstract excerpt

BACKGROUND: Systemic sclerosis (SSc) is the most severe connective tissue disorder. Recent studies have demonstrated that genetic factors may play a role in the development of SSc. The aim of this study was to investigate the association of signal transducer and activator of transcription 4 (STAT4) rs7574865 and interferon regulatory factor 5 (IRF5) rs2004640 polymorphisms with risk of SSc. METHODS: Case-control...

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PMID: 26712637
DOI: 10.1111/ijd.12839

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STAT4

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