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Article

HLA and anti-citrullinated protein antibodies: Building blocks in RA.

Best practice & research. Clinical rheumatology - 1 Dec 2015

van der Woude Diane, Catrina Anca I

Abstract excerpt

Antibodies against citrullinated proteins (ACPAs) are specific for rheumatoid arthritis (RA). ACPA-positive RA is a chronic inflammatory disease resulting from the complex interaction between genetic (mainly HLA class II genes) and environmental factors (mainly smoking). Recent findings have offered new insights into where, when and how anti-citrulline immunity develops. Some studies have found that a mucosal...

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Source

Identifiers

PMID: 27107507
DOI: 10.1016/j.berh.2016.02.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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