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Article

Autoimmunity to specific citrullinated proteins gives the first clues to the etiology of rheumatoid arthritis.

Immunological reviews - 1 Jan 2010

Wegner Natalia, Lundberg Karin, Kinloch Andrew, Fisher Benjamin, Malmström Vivianne, Feldmann Marc, Venables Patrick J

Abstract excerpt

Rheumatoid arthritis (RA) is now clearly a true autoimmune disease with accumulating evidence of pathogenic disease-specific autoimmunity to citrullinated proteins. Citrullination, also termed deimination, is a modification of arginine side chains catalyzed by peptidylarginine deiminase (PAD) enz...

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Source

Identifiers

PMID: 20192991
DOI: 10.1111/j.0105-2896.2009.00850.x

Genes

PTPN22

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20192991-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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