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The roles of anti-citrullinated protein antibodies in the immunopathogenesis of rheumatoid arthritis

14 Sept 2018

Abstract excerpt

Rheumatoid arthritis (RA) is a common systemic autoimmune disease. Its major manifestation is persistent joint inflammation, which can lead to bone destruction and severe disability. The immunopathogenesis of RA is very complex, involving both innate and adaptive immune systems. Recently, the discovery of anti-citrullinated protein antibodies (ACPAs) has revolutionized the diagnosis and our understanding of the...

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PMID: 30692825
DOI: 10.4103/tcmj.tcmj_116_18

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