Article
Apolipoprotein E (APOE) genotype and the pesticide chlorpyrifos modulate attention, motivation and impulsivity in female mice in the 5-choice serial reaction time task.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Jun 2016
Peris-Sampedro Fiona, Reverte Ingrid, Basaure Pia, Cabré Maria, Domingo José L, Colomina Maria Teresa
Abstract excerpt
Organophosphate pesticides - and chlorpyrifos (CPF) in particular - contribute to a wide range of neurobehavioural disorders. Most experimental research focuses on learning and memory processes, while other behaviours remain understudied. The isoforms of the human apolipoprotein E (apoE) confer different cognitive skills on their carriers, but data on this topic are still limited. The current study was performed...
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