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Article

Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice.

Experimental neurology - 1 Sept 2012

Reverte Ingrid, Klein Anders Bue, Ratner Cecilia, Domingo José L, Colomina Maria Teresa

Abstract excerpt

Human apolipoprotein E (apoE) plays an important role in lipid transport and distribution, being involved in neurite growth and neuroprotection in the brain. In humans, the apoE4 isoform is a risk factor for developing Azheimer's disease (AD), while apoE2 seems to provide neuroprotection. However, very little information is available on apoE2 genotype. In the present study, we have characterized behavioral and...

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Source

Identifiers

PMID: 22735491
DOI: 10.1016/j.expneurol.2012.06.015

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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