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Article

Postnatal chlorpyrifos exposure and apolipoprotein E (APOE) genotype differentially affect cholinergic expression and developmental parameters in transgenic mice.

Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association - 1 Aug 2018

Basaure Pia, Guardia-Escote Laia, Cabré Maria, Peris-Sampedro Fiona, Sánchez-Santed Fernando, Domingo José L, Colomina Maria Teresa

Abstract excerpt

Chlorpyrifos (CPF) is one of the most commonly used organophosphate pesticides in the world. Our previous results described that apolipoprotein E (APOE) polymorphisms are a source of individual differences in susceptibility to CPF. The aim of this study was to assess the physical and biochemical effects of postnatal exposure to CPF in the apoE targeted replacement mouse model. Mice were exposed to CPF at 0 or...

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Source

Identifiers

PMID: 29729306
DOI: 10.1016/j.fct.2018.04.065

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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