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Article

Inflammasome genetics contributes to the development and control of active pulmonary tuberculosis.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2016

Souza de Lima D, Ogusku M M, Sadahiro A, Pontillo A

Abstract excerpt

Tuberculosis (TB) continues to be a major public health problem. An estimated one-third of the world's population is infected with Mycobacterium tuberculosis (Mtb) but remains asymptomatic (latent TB) and only 5% to 10% of these latent individuals will develop active pulmonary TB. Factors affecting the balance between latent and active TB are mostly unknown, even if host genome has been shown to contribute to the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 27101784
DOI: 10.1016/j.meegid.2016.04.015

Genes

NLRP3
IFNG
TNF

Provenance

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