Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Roles of Inflammasomes in Host Defense against Mycobacterium tuberculosis

25 Jan 2021

Abstract excerpt

(MTB) infection is characterized by granulomatous lung lesions and systemic inflammatory responses during active disease. Inflammasome activation is involved in regulation of inflammation. Inflammasomes are multiprotein complexes serving a platform for activation of caspase-1, which cleaves the proinflammatory cytokines such as interleukin-1β (IL-1β) and IL-18 into their active forms. These cytokines play an...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autoimmune and Inflammatory Disorders Research
Share to Inflammasome and immune disorders
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33503864
DOI: 10.3390/pathogens10020120

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Roles of Inflammasomes in Host Defense against Mycobacterium tuberculosisPMID 33503864Read ↗

NLRP3 Inflammasome and Host Protection against Bacterial InfectionSemantic proximity Read ↗

Sensing pathogens and danger signals by the inflammasome.Semantic proximity Read ↗

Interaction of Mycobacteria With Host Cell InflammasomesSemantic proximity Read ↗

Regulation of inflammasome activation.Semantic proximity Read ↗

Virulent Mycobacterium bovis Beijing Strain Activates the NLRP7 Inflammasome in THP-1 MacrophagesSemantic proximity Read ↗

Inflammasomes and Their Roles in Health and DiseaseSemantic proximity Read ↗

Can We Exploit Inflammasomes for Host-Directed Therapy in the Fight against Mycobacterium tuberculosis Infection?Semantic proximity Read ↗

Mechanisms and Functions of InflammasomesSemantic proximity Read ↗

NLRP3 Inflammasome—A Key Player in Antiviral ResponsesSemantic proximity Read ↗

Mycobacterium Tuberculosis Infection and Inflammation: what is Beneficial for the Host and for the Bacterium?Semantic proximity Read ↗

Inflammasomes and host defenses against bacterial infectionsSemantic proximity Read ↗

NLRP11 is required for canonical NLRP3 and non-canonical inflammasome activation during human macrophage infection with mycobacteriaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.