Article
The association of inflammasome and TLR2 gene polymorphisms with susceptibility to tuberculosis in the Han Taiwanese population.
Scientific reports - 23 Jun 2020
Liu Chi-Wei, Lin Chou-Jui, Hu Hui-Chun, Liu Hsiu-Jung, Chiu Yu-Chi, Lee Shih-Wei, Wu Lawrence Shih-Hsin
Abstract excerpt
Pulmonary tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is a global public health concern. Although inflammasome and the toll-like receptor 2 (TLR2) genes play an important role in host defense against Mtb, the associations of polymorphisms in these genes with TB risk are incompletely understood. A total of 230 TB patients and 213 individuals without TB were enrolled in this study. A significant...
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