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Article

Innate immune gene polymorphisms in tuberculosis.

Infection and immunity - 1 Oct 2012

Azad Abul K, Sadee Wolfgang, Schlesinger Larry S

Abstract excerpt

Tuberculosis (TB) is a leading cause worldwide of human mortality attributable to a single infectious agent. Recent studies targeting candidate genes and "case-control" association have revealed numerous polymorphisms implicated in host susceptibility to TB. Here, we review current progress in the understanding of causative polymorphisms in host innate immune genes associated with TB pathogenesis. We discuss...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Polymorphism, Genetic

Share to Receptors, Pattern Recognition

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Source

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Identifiers

PMID: 22825450
DOI: 10.1128/IAI.00443-12
PMCID: PMC3457569

Genes

CXCL10
NOD1
NOD2
TNF
VDR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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