Article
Understanding of HLA-conferred susceptibility to chronic hepatitis B infection requires HLA genotyping-based association analysis.
Scientific reports - 19 Apr 2016
Nishida Nao, Ohashi Jun, Khor Seik-Soon, Sugiyama Masaya, Tsuchiura Takayo, Sawai Hiromi, Hino Keisuke, Honda Masao, Kaneko Shuichi, Yatsuhashi Hiroshi, Yokosuka Osamu, Koike Kazuhiko, Kurosaki Masayuki, Izumi Namiki, Korenaga Masaaki, Kang Jong-Hon, Tanaka Eiji, Taketomi Akinobu, Eguchi Yuichiro, Sakamoto Naoya, Yamamoto Kazuhide, Tamori Akihiro, Sakaida Isao, Hige Shuhei, Itoh Yoshito, Mochida Satoshi, Mita Eiji, Takikawa Yasuhiro, Ide Tatsuya, Hiasa Yoichi, Kojima Hiroto, Yamamoto Ken, Nakamura Minoru, Saji Hiroh, Sasazuki Takehiko, Kanto Tatsuya, Tokunaga Katsushi, Mizokami Masashi
Abstract excerpt
Associations of variants located in the HLA class II region with chronic hepatitis B (CHB) infection have been identified in Asian populations. Here, HLA imputation method was applied to determine HLA alleles using genome-wide SNP typing data of 1,975 Japanese individuals (1,033 HBV patients and 942 healthy controls). Together with data of an additional 1,481 Japanese healthy controls, association tests of six...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.