Article
Evaluation of genetic susceptibility loci for chronic hepatitis B in Chinese: two independent case-control studies.
PloS one - 8 Mar 2011
Wang Li, Wu Xiao-Pan, Zhang Wei, Zhu Da-Hai, Wang Ying, Li Yan-Ping, Tian Yao, Li Rong-Cheng, Li Zhuo, Zhu Xinlin, Li Jun-Hong, Cai Jun, Liu Li, Miao Xiao-Ping, Liu Ying, Li Hui
Abstract excerpt
BACKGROUND: A recent genome-wide scan has identified two genetic variants in the HLA-DP region strongly associated with hepatitis B infection in Japanese. This study evaluates the effects of these risk variants in Chinese, where the HBV infection is the most popular in the world. METHODS AND FINDINGS: We have assessed the relationship between these two single nucleotide polymorphisms (rs3077 and rs9277535) and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
