Article
Fine mapping analysis of HLA-DP/DQ gene clusters on chromosome 6 reveals multiple susceptibility loci for HBV infection.
Amino acids - 1 Dec 2015
Tao Jingjing, Su Kunkai, Yu Chengbo, Liu Xiaoli, Wu Wei, Xu Wei, Jiang Bingxun, Luo Rui, Yao Jian, Zhou Jiawei, Zhan Yan, Ye Chao, Yuan Wenji, Jiang Xianzhong, Cui Wenyan, Li Ming D, Li Lianjuan
Abstract excerpt
Recent genome-wide association studies have revealed the HLA region on chromosome 6p21 as a susceptibility locus for hepatitis B virus (HBV) infection, a finding subsequently replicated in independent samples. However, only limited single nucleotide polymorphisms (SNPs) were analyzed in most of these studies, and it remains to be determined which SNPs contribute to the detected association. After genotyping 140...
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