Article
Increased CD56(bright) NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype.
Virology journal - 18 Apr 2016
Bhardwaj Suvercha, Ahmad Fareed, Wedemeyer Heiner, Cornberg Marcus, Schulze Zur Wiesch Julian, van Lunzen Jan, Sarin Shiv K, Schmidt Reinhold E, Meyer-Olson Dirk
Abstract excerpt
BACKGROUND: HIV-HCV co-infection is associated with accelerated progression to hepatic fibrosis, cirrhosis and hepatocellular carcinoma than HCV mono-infection. The contribution of innate immunity during HIV-HCV co-infection has been a relatively under-investigated area. Natural killer (NK) cells are pivotal sentinels of innate immunity against viruses and tumour cells. In this study we evaluated the effect of...
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