Article
Differential alteration of CD56(bright) and CD56 (dim) natural killer cells in frequency, phenotype, and cytokine response in chronic hepatitis C virus infection.
Journal of gastroenterology - 1 Aug 2011
Miyagi Takuya, Shimizu Satoshi, Tatsumi Tomohide, Nishio Kumiko, Hiramatsu Naoki, Kanto Tatsuya, Hayashi Norio, Takehara Tetsuo
Abstract excerpt
BACKGROUND: Natural killer (NK) cells play an important role in immune responses to virus infection. The cell population consists of CD56(bright) (bright-subset) and CD56(dim) (dim-subset) subsets that possess armed functions of cytokine production and cytolysis, respectively. How these subsets are involved in chronic hepatitis C virus infection (CHC) remains obscure. METHODS: We investigated the frequency,...
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