Article
NK cell phenotypic profile during active TB in people living with HIV-evolution during TB treatment and implications for bacterial clearance and disease severity.
Scientific reports - 20 Jul 2023
Maseko Thando Glory, Rambaran Santhuri, Ngubane Slindile, Lewis Lara, Ngcapu Sinaye, Hassan-Moosa Razia, Archary Derseree, Perumal Rubeshan, Padayatchi Nesri, Naidoo Kogieleum, Sivro Aida
Abstract excerpt
Natural killer (NK) cells, key effector cells of the innate immune system, play an important role in the clearance and control of Mycobacterium tuberculosis and HIV infections. Here, we utilized peripheral blood specimens from the Improving Retreatment Success CAPRISA 011 study to characterize NK cell phenotypes during active TB in individuals with or without HIV co-infection. We further assessed the effects of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.