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Article

Killer Ig-like receptor (KIR) genotype predicts the capacity of human KIR-positive CD56dim NK cells to respond to pathogen-associated signals.

Journal of immunology (Baltimore, Md. : 1950) - 15 May 2009

Korbel Daniel S, Norman Paul J, Newman Kirsty C, Horowitz Amir, Gendzekhadze Ketevan, Parham Peter, Riley Eleanor M

Abstract excerpt

IFN-gamma emanating from NK cells is an important component of innate defense against infection. In this study, we demonstrate that, following in vitro stimulation of human peripheral blood NK cells with a variety of microbial ligands, CD56(dim) as well as CD56(bright) NK cells contribute to the overall NK cell IFN-gamma response with, for most cell donors, IFN-gamma(+) CD56(dim) NK cells outnumbering...

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Share to Antigens, Bacterial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 19414796
DOI: 10.4049/jimmunol.0804224
PMCID: PMC2854670

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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