Article
Chronic HCV infection affects the NK cell phenotype in the blood more than in the liver.
PloS one - 1 Jan 2014
Cosgrove Cormac, Berger Christoph T, Kroy Daniela C, Cheney Patrick C, Ghebremichael Musie, Aneja Jasneet, Tomlinson Michelle, Kim Arthur Y, Lauer Georg M, Alter Galit
Abstract excerpt
Although epidemiological and functional studies have implicated NK cells in protection and early clearance of HCV, the mechanism by which they may contribute to viral control is poorly understood, particularly at the site of infection, the liver. We hypothesized that a unique immunophenotypic/functional NK cell signature exists in the liver that may provide insights into the contribution of NK cells to viral...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.