Article
A specific natural killer cells phenotypic signature associated to long term elite control of HIV infection.
Journal of medical virology - 1 May 2024
Rallón Norma, Jiménez-Carretero Daniel, Restrepo Clara, Ligos José M, Valentín-Quiroga Jaime, Mahillo Ignacio, Cabello Alfonso, López-Collazo Eduardo, Sánchez-Cabo Fátima, Górgolas Miguel, Estrada Vicente, Benito José M
Abstract excerpt
Elite controllers (ECs) are an exceptional group of people living with HIV (PLWH) that control HIV replication without therapy. Among the mechanisms involved in this ability, natural killer (NK)-cells have recently gained much attention. We performed an in-deep phenotypic analysis of NK-cells to search for surrogate markers associated with the long term spontaneous control of HIV. Forty-seven PLWH (22 long-term...
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