Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence.

Behavior genetics - 1 Sept 2016

Kamens Helen M, Corley Robin P, Richmond Phillip A, Darlington Todd M, Dowell Robin, Hopfer Christian J, Stallings Michael C, Hewitt John K, Brown Sandra A, Ehringer Marissa A

Abstract excerpt

Common SNPs in nicotinic acetylcholine receptor genes (CHRN genes) have been associated with drug behaviors and personality traits, but the influence of rare genetic variants is not well characterized. The goal of this project was to identify novel rare variants in CHRN genes in the Center for Antisocial Drug Dependence (CADD) and Genetics of Antisocial Drug Dependence (GADD) samples and to determine if low...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to Antisocial Personality Disorder

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Genetic Association Studies

Share to Quality Control

Share to Receptors, Nicotinic

Share to Software

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 27085880
DOI: 10.1007/s10519-016-9792-4
PMCID: PMC4975622

Genes

CHRNA6
CHRNB3
CHRNA1
CHRNB1
CHRND
CHRNE
CHRNG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Evidence for Association Between Low Frequency Variants in CHRNA6/CHRNB3 and Antisocial Drug Dependence.PMID 27085880Read ↗

Nominal association with CHRNA4 variants and nicotine dependence.Semantic proximity Read ↗

Rare missense variants in CHRNB3 and CHRNA3 are associated with risk of alcohol and cocaine dependence.Semantic proximity Read ↗

Introduction to deep sequencing and its application to drug addiction research with a focus on rare variants.Semantic proximity Read ↗

Rare nonsynonymous exonic variants in addiction and behavioral disinhibition.Semantic proximity Read ↗

Common single nucleotide variants underlying drug addiction: more than a decade of research.Semantic proximity Read ↗

Resequencing of nicotinic acetylcholine receptor genes and association of common and rare variants with the Fagerström test for nicotine dependence.Semantic proximity Read ↗

Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence.Semantic proximity Read ↗

Genetic association of the CHRNA6 and CHRNB3 genes with tobacco dependence in a nationally representative sample.Semantic proximity Read ↗

Investigating CHRNA5, CHRNA3, and CHRNB4 variants in the genetic landscape of substance use disorder in Jordan.Semantic proximity Read ↗

Associations of rare nicotinic cholinergic receptor gene variants to nicotine and alcohol dependence.Semantic proximity Read ↗

Differential contribution of genetic variation in multiple brain nicotinic cholinergic receptors to nicotine dependence: recent progress and emerging open questions.Semantic proximity Read ↗

Association of candidate genes with antisocial drug dependence in adolescents.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.