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Article

Investigating CHRNA5, CHRNA3, and CHRNB4 variants in the genetic landscape of substance use disorder in Jordan.

BMC psychiatry - 11 Jun 2024

Al-Eitan Laith, Shatnawi Mohammad, Alghamdi Mansour

Abstract excerpt

BACKGROUND: Substance use disorder (SUD) is a complex illness that can be attributed to the interaction between environmental and genetic factors. The nicotinic receptor gene cluster on chromosome 15 has a plausible association with SUD, particularly with nicotine dependence. METHODS: This study investigated 15 SNPs within the CHRNA5, CHRNA3, and CHRNB4 genes. Sequencing was used for genotyping 495 Jordanian...

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Identifiers

PMID: 38862938
DOI: 10.1186/s12888-024-05898-7
PMCID: PMC11167846

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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